THE BONE MARROW OF MYELOMA PATIENTS IS STEADILY INHABITED BY A NORMAL-SIZED POOL OF FUNCTIONAL REGULATORY T CELLS IRRESPECTIVEOF THE DISEASE STATUS

The bone marrow of myeloma patients is steadily inhabited by a normal-sized pool of functional regulatory T cells irrespectiveof the disease status

Conflicting data have been reported about the frequency and function of regulatory T cells in multiple myeloma.Most studies have investigated peripheral blood rather than bone marrow Tregs and side-by-side comparisons with bone marrow from healthy donors have still not been made.In this study, we show that regulatory T-cells total count, subset dis

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The Role of Neutrophil Extracellular Traps in Periodontitis

Periodontitis is a chronic, destructive disease of periodontal tissues caused by multifaceted, dynamic interactions.Periodontal bacteria and host immunity jointly contribute to the pathological processes of the disease.The dysbiotic microbial communities elicit an excessive immune response, mainly by polymorphonuclear neutrophils (PMNs).As one of t

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